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Prof. Ken Herrmann, director of the Department of Nuclear Medicine at University Hospital Essen, pictured fourth from the left, at the opening opening of a new nuclear medicine center in Essen, Germany, focused on theranostics and personalized cancer care.

Q&A with Ken Herrmann: Theranostics must move earlier and beyond established targets

Prof. Ken Herrmann discusses the expansion of radioligand therapy into earlier treatment lines, the need for new cancer targets, long-term safety, and the challenge of translating innovation into robust clinical evidence.

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Example of AI-assisted pulmonary nodule detection and longitudinal volumetric assessment in a 65-year-old woman with peripheral arterial disease, a 24-pack-year smoking history, emphysema, and a family history of lung cancer. An incidental 8.5-mm right lower lobe pulmonary nodule is identified at CT angiography of the abdomen in July 2022 but does not receive follow-up. Subsequent imaging demonstrates interval growth, and CT-guided biopsy confirms stage IA lung adenocarcinoma. Contrast-enhanced axial chest CT images obtained on February 2, 2024, before robotic-assisted thoracoscopic segmentectomy, show a 12.1-mm spiculated right lower lobe pulmonary nodule. (A) Conventional contrast-enhanced axial chest CT image without AI assistance shows a 12.1-mm spiculated right lower lobe pulmonary nodule. (B) Corresponding CT image with AI-assisted pulmonary nodule detection, automated segmentation, and quantitative nodule assessment identifies a solid pulmonary nodule (nodule #1) measuring 13 × 8 (11) mm, with a volume of 739 mm3, a 45% volumetric increase compared with the previous contrast-enhanced chest CT performed on October 9, 2023 (510 mm3), and an estimated volume doubling time (VDT) of 216 days. (C) AI-generated longitudinal nodule analysis displays automated segmentation of the current (February 2, 2024) and previous (October 9, 2023) CT examinations, 3D nodule reconstruction, and quantitative volumetric assessment for longitudinal follow-up. The AI interface is displayed in the original software language (Dutch).

AI cuts chest CT reporting time

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Video: Ken Herrmann maps nuclear medicine’s next frontiers

This figure shows fused I-124 evuzamitide positron emission tomography (PET)/computed tomography (CT) images from patients without amyloidosis and from patients with ATTR cardiac amyloidosis, early ATTR cardiac amyloidosis, light chain cardiac amyloidosis, gelsolin-mediated amyloidosis, and systemic organ amyloid. The columns represent radiological transaxial, sagittal, and coronal views except for the last row middle and far right columns, which are coronal projections. The blue asterisks represent physiological activity (tracer activity in the stomach and esophagus). The arrowheads represent pathological uptake. Note the small amount of cardiac uptake in the basal septum and the basal lateral walls (likely early ATTR cardiac amyloidosis), splenic uptake and pleural uptake in light chain amyloidosis, and cardiac and kidney uptake in gelsolin-mediated amyloidosis. The bright yellow color represents more tracer uptake.

Bayer's PET agent meets endpoints in phase III cardiac amyloidosis study

August 31, 2026

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SPECT, PET refine contemporary cardiac amyloidosis assessment

August 24, 2026

Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.

Advanced ultrasound techniques improve soft tissue tumor evaluation

August 26, 2026

Antoine Leimgruber

Swiss nuclear medicine seeks rules fit for radiopharmaceutical innovation

August 27, 2026

Check out our Cases of the Week!

Patient with abdominal pain revisited

A patient with abdominal pain out of proportion to the exam.

39-year-old man with chronic abdominal pain revisited

83-year-old female former smoker with imaging follow-up revisited

Prof. Ken Herrmann, director of the Department of Nuclear Medicine at University Hospital Essen, pictured fourth from the left, at the opening opening of a new nuclear medicine center in Essen, Germany, focused on theranostics and personalized cancer care.

Q&A with Ken Herrmann: Theranostics must move earlier and beyond established targets

AI cuts chest CT reporting time

Bayer's PET agent meets endpoints in phase III cardiac amyloidosis study

Video: Ken Herrmann maps nuclear medicine’s next frontiers

SPECT, PET refine contemporary cardiac amyloidosis assessment

Low-quality axial T2-weighted MRI scans with gradient-weighted class activation mapping. The low-quality MRI scans (top row) show blurred structures and artifacts making zonal and capsule boundaries indistinguishable. On the same scans with gradient-weighted class activation map overlays (bottom row), red indicates regions that were most heavily weighted by the deep learning model toward the low-quality prediction.

AI framework could improve MRI quality control in prostate cancer

Review highlights opportunities and risks of AI in pediatric imaging

AI performs well in breast screening, but density complicates the picture

EU AI Act brings radiology AI oversight into daily practice

Radiologists can identify three out of four AI-generated images

Bir Full Colour

BIR signs three-year collaboration agreement with IAEA

GEHC's Photonova Spectra photon-counting CT receives CE Mark

GEHC adds three systems to Vivid ultrasound portfolio

Nanox AI signs distribution deal for HealthOST software

Radiology Partners to acquire Everlight Radiology in $1 billion deal

ECR: Cardiac imaging is at the 'heart' of precision medicine

By Kate Madden Yee

The heart beats 2.5 billion times in a person's lifetime and "never has a day off," presenter Prof. Michelle Williams, PhD, noted.

March 6, 2026

ECR: Does AI toll the beginning of the end for chest x-ray reporting?

By Frances Rylands-Monk

A presentation at ECR 2026 assessed the future of chest x-rays in Europe and the role of AI.

March 6, 2026

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ECR: AI comparable to radiologists in detecting foot fractures

The findings support the use of AI as complementary help for radiologists in a busy workflow.

March 6, 2026

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Video from ECR: Andrea Rockall on EU advocacy, sustainability

By Erik L. Ridley

ESR Chairperson Prof. Andrea Rockall shared her perspective on a range of topics, including sustainability and the importance of radiologist advocacy.

March 6, 2026

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Greek gods and the ECR 2026 opening ceremony

This year's theme for the congress is "Rays of Knowledge," with Athena, the ancient Greek goddess of knowledge and wisdom, as the event’s symbol.

March 6, 2026

ECR: Imaging biomarker studies need stronger quality assurance

Prof. Fiona Gilbert shares lessons learned from two important studies.

March 6, 2026

ECR: LLMs help patients understand breast imaging reports

By Amerigo Allegretto

Dr. Hemal Grover shared results from two studies of how LLMs can improve report readability for patients.

March 6, 2026

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ECR: What's the follow-up when radiologists reject AI findings?

Radiologists are working toward systematic processes for AI disagreement.

March 6, 2026

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Video from ECR: Young radiologists should drive change, not adapt to it

By Claudia Tschabuschnig

Young radiologists must not only adapt to rapid technological change but also actively help shape the future of the field, says Prof. Ioana Gheonea, chair of the Young ESR Committee, in a video interview at ECR 2026.

March 6, 2026

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Video from ECR: 'The Stone Age didn’t end because of a lack of stones'

In an interview at ECR, Dr. Andrei Iagaru, discussed the status of gamma-emitting imaging in theranostics and its future potential.

March 6, 2026

Sectra to acquire AI radiology developer Oxipit

By AuntMinnieEurope.com staff writers

Sectra will acquire Oxipit, a developer of AI tools for x-ray and CT analyses.

March 5, 2026

Sectra Rsna 2019 400

Video from ECR: Minerva Becker shares congress highlights

By Erik L. Ridley

In a video interview, ESR President Prof. Minerva Becker discussed important themes at ECR 2026, developments with the "Modern Radiology eBook," and take-home messages for attendees.

March 5, 2026

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