Computer-aided detection (CAD) software developer iCAD has received the CE Mark for version 3.0 of its ProFound AI for digital breast tomosynthesis (DBT) software.
The new release delivers a 10% improvement in specificity while maintaining the software's high sensitivity, according to the vendor. In addition, ProFound AI for DBT 3.0 features 40% faster processing times on the company's new PowerLook platform, iCAD said.
After analyzing each DBT image, the software detects malignant soft-tissue densities and calcifications, assigning "certainty of finding" for each detection, and it also provides an overall score for each case that represents the algorithm's confidence of malignancy.
![A normal mammogram confirmed by three-year radiologic follow-up illustrates reader-marked regions of interest (ROIs) during (A) unaided (round 1) and (B) artificial intelligence (AI)–assisted (round 2) reading. Each colored dot represents an ROI for recall by a human reader. Readers could mark more than one ROI per case, represented by multiple dots of the same color. During AI-assisted reading, the AI system displayed three visible prompts: two with suspicion of malignancy scores of 35% (left mediolateral oblique [L MLO] and craniocaudal [L CC]) and one with a suspicion of malignancy score of 10% (right craniocaudal [R CC]), shown as polygonal overlays. Without AI, six of 10 readers (60%) marked a false-positive ROI. With AI assistance, this fell to two of 10 (20%). R MLO = right mediolateral oblique.](https://img.auntminnieeurope.com/mindful/smg/workspaces/default/uploads/2026/07/2026-07-14-radiology-mammogram-ai-auto-bias.H0bYO8QlWs.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
