Dr. J. Leonard Lichtenfeld

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Prostate Cancer 400
MRI
MRI could replace DRE for prostate cancer staging
MRI showed comparable performance to DRE in prostate cancer staging without compromising patient outcomes.
A normal mammogram confirmed by three-year radiologic follow-up illustrates reader-marked regions of interest (ROIs) during (A) unaided (round 1) and (B) artificial intelligence (AI)–assisted (round 2) reading. Each colored dot represents an ROI for recall by a human reader. Readers could mark more than one ROI per case, represented by multiple dots of the same color. During AI-assisted reading, the AI system displayed three visible prompts: two with suspicion of malignancy scores of 35% (left mediolateral oblique [L MLO] and craniocaudal [L CC]) and one with a suspicion of malignancy score of 10% (right craniocaudal [R CC]), shown as polygonal overlays. Without AI, six of 10 readers (60%) marked a false-positive ROI. With AI assistance, this fell to two of 10 (20%). R MLO = right mediolateral oblique.
Womens Imaging
Incorrect AI suggestions influence reader performance on mammography
Iodinated contrast media are among the most commonly administered agents in radiology.
CT
Large Korean study adds evidence on contrast media hypersensitivity
Voxel-based morphometry (VBM) group comparison of grey matter brain volumes. TFCE-corrected significance map shown (one-tailed t-test; higher significance indicated by light blue color). (a) Comparison between ex-soccer players (n = 124) and controls (n = 40). (b) Comparison between ex-rugby players (n = 200) and controls (n = 33) from Graham & Zimmerman et al. (2025), reproduced with permission under Creative Commons license.
MRI
MRI shows higher neuro symptom burden for former football players
Surgeon performs a carotid artery procedure.
Interventional Radiology
German registry shows sharp rise in carotid artery stenting as CREST-2 reshapes prevention
More in Home
MRI could replace DRE for prostate cancer staging
By Amerigo Allegretto
MRI showed comparable performance to DRE in prostate cancer staging without compromising patient outcomes.
July 15, 2026
Prostate Cancer 400
Incorrect AI suggestions influence reader performance on mammography
By Amerigo Allegretto
The biggest impact on reader performance stemmed from false-negative AI suggestions.
July 14, 2026
A normal mammogram confirmed by three-year radiologic follow-up illustrates reader-marked regions of interest (ROIs) during (A) unaided (round 1) and (B) artificial intelligence (AI)–assisted (round 2) reading. Each colored dot represents an ROI for recall by a human reader. Readers could mark more than one ROI per case, represented by multiple dots of the same color. During AI-assisted reading, the AI system displayed three visible prompts: two with suspicion of malignancy scores of 35% (left mediolateral oblique [L MLO] and craniocaudal [L CC]) and one with a suspicion of malignancy score of 10% (right craniocaudal [R CC]), shown as polygonal overlays. Without AI, six of 10 readers (60%) marked a false-positive ROI. With AI assistance, this fell to two of 10 (20%). R MLO = right mediolateral oblique.
Large Korean study adds evidence on contrast media hypersensitivity
By Claudia Tschabuschnig
A Korean study of almost 116,000 contrast media recipients adds new evidence on hypersensitivity risk factors, but a European expert says the findings should be interpreted in the context of current European practice.
July 14, 2026
Iodinated contrast media are among the most commonly administered agents in radiology.
MRI shows higher neuro symptom burden for former football players
By Amerigo Allegretto
Former elite football players have lower white matter volume and report higher levels of depression and anxiety.
July 13, 2026
Voxel-based morphometry (VBM) group comparison of grey matter brain volumes. TFCE-corrected significance map shown (one-tailed t-test; higher significance indicated by light blue color). (a) Comparison between ex-soccer players (n = 124) and controls (n = 40). (b) Comparison between ex-rugby players (n = 200) and controls (n = 33) from Graham & Zimmerman et al. (2025), reproduced with permission under Creative Commons license.
German registry shows sharp rise in carotid artery stenting as CREST-2 reshapes prevention
By Claudia Tschabuschnig
German hospitals performed a record 5,623 carotid artery stenting procedures in 2025, with new registry data and findings from the CREST-2 trial highlighting the evolving management of asymptomatic carotid stenosis.
July 13, 2026
Surgeon performs a carotid artery procedure.
CEM on par with MRI for breast cancer diagnosis, local staging
By Amerigo Allegretto
CEM alone in a prospective study achieved perfect sensitivity and negative predictive value in diagnosing breast cancer.
July 10, 2026
MRI false positive for additional disease, (top to bottom): A. Index lesion—grade 2 invasive ductal carcinoma; B. MRI lesion two, upper inner quadrant: Stromal sclerosis and columnar cell change; C. MRI lesion three, upper outer quadrant: No ultrasound correlate, no malignancy on follow-up; D. CEM marked background parenchymal enhancement with a unifocal retroareolar lesion demonstrating wash-out on delayed MLO. Images are republished under a Creative Commons license (CC BY 4.0).
New PET tracer show promise in neuroblastoma
By Will Morton
F-18 mFBG achieved a pooled sensitivity of 97%, compared with 82% for I-123 MIBG.
July 9, 2026
Cancer Target
The cost of AI, and finding its breakeven point
By Claudia Tschabuschnig
Who pays, what, where, and when: speakers at the Royal College of Radiologists' Global AI Conference dug into what AI actually costs and when, if ever, it pays for itself.
July 9, 2026
Who's paying, and for what, is the question that actually decides whether AI in healthcare gets funded.
AI aims to decode targeted radiotherapy response
By Claudia Tschabuschnig
Same administered activity, different results. Speakers at the Royal College of Radiologists’ 2nd Annual Global AI Conference argued AI could help move targeted radionuclide therapy beyond a one-size-fits-all approach toward more precise, personalized treatment.
July 8, 2026
Experts at the Royal College of Radiologists’ 2nd Annual Global AI Conference discussed how AI could help move cancer care toward more personalized treatment, from targeted radionuclide therapy dosing to drug discovery.
RCR: Agentic AI is off the leash, and already a workhorse for health systems
By Claudia Tschabuschnig
The technical crowd took the stage at the 2nd Annual Global AI Conference in London last week, to show radiologists where agentic AI is running, how it operates across a spread of autonomy, and why only the highest tiers demand serious governance.
July 7, 2026
Dr. Rowland Illing, chief medical officer at Amazon Web Services (AWS) and a former interventional radiologist.
PET/MRI can reduce the need for biopsies in prostate cancer
By Will Morton
Prostate biopsies are associated with considerable morbidity, including pain, rectal bleeding, prostatitis, and urinary tract infections.
July 2, 2026
A visual abstract of the study.
Imaging takes center stage in Europe's Safe Hearts Plan
By Claudia Tschabuschnig
Radiology and nuclear medicine are poised to play a central role in implementing the European Commission's Safe Hearts Plan, speakers said during a joint ESR/EANM event in Brussels.
July 2, 2026
The Safe Hearts Plan aims to shift healthcare systems toward prevention, earlier diagnosis, and more personalized care.
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