Le professeur Denis Le Bihan a reçu la prestigieuse médaille Antoine Béclère le jour de l'ouverture des Journées Francophones de Radiologie (JFR 2022). Dans cette interview vidéo exclusive réalisée sur place, il s'est entretenu avec la correspondante Mélisande Rouger sur le potentiel clinique de l'IRM de diffusion, les efforts de son équipe pour développer un scanner IRM dédié au dépistage du cancer du sein, et les progrès réalisés sur la machine prototype de 11,7 teslas.
"Ce prix représente beaucoup," a-t-il déclaré. "Antoine Béclère a créé la Société parisienne de radiologie, qui est devenue la SFR, en 1909. C'est le père de la radiologie française."
Le prix est une reconnaissance de 40 années consacrées à l'avancement de l'IRM de diffusion, qui a permis le développement d'un traitement pour les accidents vasculaires cérébraux aigus, a noté Le Bihan.
"Nous pouvons sauver la vie des patients victimes d'un AVC, et cela a commencé avec l'IRM de diffusion." Il ajoute que l'IRM a une bien meilleure sensibilité que la mammographie, mais qu'elle n'est pas aussi largement disponible et est en proie à des problèmes de produits de contraste à base de gadolinium.
"Mon rêve est de fabriquer un système d'IRM dédié au sein, très petit et bon marché, qui pourrait être utilisé pour le dépistage (...). Il pourrait remplacer la mammographie."
Le professeur Denis Le Bihan nous livre ses réflexions sur l'IRM de diffusion, le dépistage du cancer du sein et ses morceaux de piano préférés lors du congrès national français de radiologie, les JFR 2022.
Note de rédacteur: Ceci est une traduction éditée d'un article publié en anglais en ligne par AuntMinnieEurope. Traduction par Frances Rylands-Monk.
![Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.](https://img.auntminnieeurope.com/mindful/smg/workspaces/default/uploads/2026/08/images-radiol250278fig2.APCFLSvX6p.jpg?auto=format%2Ccompress&fit=crop&h=100&q=70&w=100)
![Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.](https://img.auntminnieeurope.com/mindful/smg/workspaces/default/uploads/2026/08/images-radiol250278fig2.APCFLSvX6p.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
