Proton therapy developer Ion Beam Applications (IBA) signed a contract with CYCLHAD (a cyclotron for hadron therapy) for the installation of its single-room proton therapy system ProteusOne in Caen, France.
The contract includes ProteusOne equipment delivery and a 15-year maintenance agreement, which together will have a value of between 43 million euros and 48 million euros to IBA. The delivery of the equipment is expected to take place in 2017, the firm said.
This is the seventh installation of a ProteusOne.
In a second phase of development, IBA will collaborate with several French industrial partners and semipublic institutions to develop the potential of carbon beam therapy. IBA will provide support and expertise for the development of a prototype carbon therapy system based on an advanced 400-megaelectron-volts superconducting isochronous cyclotron able to accelerate carbon ions used in hadron therapy.
![Overview of the study design. (A) The fully automated deep learning framework was developed to estimate body composition (BC) (defined as subcutaneous adipose tissue [SAT] in liters; visceral adipose tissue [VAT] in liters; skeletal muscle [SM] in liters; SM fat fraction [SMFF] as a percentage; and intramuscular adipose tissue [IMAT] in deciliters) from MRI. The fully automated framework comprised one model (model 1) to quantify different BC measures (SAT, VAT, SM, SMFF, and IMAT) as three-dimensional (3D) measures from whole-body MRI scans. The second model (model 2) was trained to identify standardized anatomic landmarks along the craniocaudal body axis (z coordinate field), which allowed for subdividing the whole-body measures into different subregions typically examined on clinical routine MRI scans (chest, abdomen, and pelvis). (B) BC was quantified from whole-body MRI in over 66,000 individuals from two large population-based cohort studies, the UK Biobank (UKB) (36,317 individuals) and the German National Cohort (NAKO) (30,291 individuals). Bar graphs show age distribution by sex and cohort. BMI = body mass index. (C) After the performance assessment of the fully automated framework, the change in BC measures, distributions, and profiles across age decades were investigated. Age-, sex-, and height-adjusted body composition reference curves were calculated and made publicly available in a web-based z-score calculator (https://circ-ml.github.io).](https://img.auntminnieeurope.com/mindful/smg/workspaces/default/uploads/2026/05/body-comp.XgAjTfPj1W.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
