Similar outcomes for patients after laparoscopic and open colorectal cancer resection


NEW YORK (Reuters Health), Jun 6 - Laparoscopic colorectal cancer resection and open colectomy provide similar long-term patient outcomes, according to a new report.

Laparoscopic resection of colorectal cancer is not performed commonly, the authors explain, because of concerns about oncological radicality and long-term outcome, according to the findings in the April 16 issue of the Cochrane Database of Systematic Reviews.

Dr. Esther Kuhry from Namsos Hospital in Norway and colleagues evaluated the long-term results of laparoscopic and conventional colorectal resection in a systematic review of 12 randomized, controlled trials containing 3,346 patients.

There were no significant differences between laparoscopic and open surgery in the occurrence of incisional hernia, the number of reoperations for incisional hernia, or the number of reoperations for intraperitoneal adhesions, the authors report.

Recurrences at the site of the primary tumor, the occurrence of port-site and wound metastases or peritoneal metastases, and the development of distant metastases did not differ between laparoscopic and open surgery, overall or when colon and rectal cancer were analyzed separately.

Cancer-related mortality and overall mortality were similar after laparoscopic and open surgery, the researchers note. Mortality rates did not differ for colon cancer, but there were insufficient data to analyze rectal cancer survival separately.

"Laparoscopic surgery for colon cancer is a safe procedure that is associated with a survival rate equal to survival after open surgery," the investigators conclude. "The procedure can therefore be offered routinely to patients in hospitals where surgeons with sufficient experience in laparoscopic colon surgery are available."

"In the case of rectal cancer," they add, "data on long-term outcome are scarce and the results of large randomized trials have to be awaited."

Cochrane Database of Systematic Reviews 2008; Art. No. CD003432.

Last Updated: 2008-06-05 13:26:14 -0400 (Reuters Health)

Related Reading

Laparoscopic-assisted surgery provides good long-term outcomes in colon cancer, August 3, 2007

Copyright © 2008 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

Page 1 of 1234
Next Page