Marric Stephens[email protected]Clinical NewsCT-based radiomics reveals prostate cancer riskUsing machine learning, U.K. and Dutch researchers have developed prediction models to identify textural and intensity-based features imperceptible to human observers, and to associate them with commonly used measures of disease progression in prostate cancer.September 5, 2019Clinical NewsGermans use spectroscopy to cut beam-range uncertaintyGerman scientists are convinced that measuring the energy of gamma rays emitted during helium-ion radiotherapy can provide real-time verification of the beam's range in the patient. They have shown how to define the size of the range error in particle therapy, allowing more precise treatments with greater sparing of healthy tissue.July 4, 2019Clinical NewsDual-energy CT for proton therapy planning reaches clinicGerman researchers have introduced a technique for more accurate proton therapy planning into routine clinical use. They are implementing a novel, patient-specific method of proton range prediction based on dual-energy CT.June 13, 2019Clinical NewsDual detector combines nuclear and fluoroscopic imagingDutch researchers have demonstrated the feasibility of using a flat-panel x-ray detector combined with a gamma camera to allow simultaneous acquisition of fluoroscopic and nuclear images. The instrument could provide clinicians with anatomical information not currently available using nuclear imaging alone.February 14, 2019Page 1 of 1Top StoriesMRIMRI reveals how hidden muscle fat increases risk to heart, metabolismThe results suggest that MRI exams could "augment traditional risk factor screening," researchers noted.Molecular ImagingThe EANM joins EMUC26 and pushes its policy agenda in BrusselsMRIWhole body MRI, deep-learning can 'map' distribution of fat and muscleCTFirst signals from Germany's lung cancer screeningSponsor ContentTurning Innovation into Everyday Efficiency
![Overview of the study design. (A) The fully automated deep learning framework was developed to estimate body composition (BC) (defined as subcutaneous adipose tissue [SAT] in liters; visceral adipose tissue [VAT] in liters; skeletal muscle [SM] in liters; SM fat fraction [SMFF] as a percentage; and intramuscular adipose tissue [IMAT] in deciliters) from MRI. The fully automated framework comprised one model (model 1) to quantify different BC measures (SAT, VAT, SM, SMFF, and IMAT) as three-dimensional (3D) measures from whole-body MRI scans. The second model (model 2) was trained to identify standardized anatomic landmarks along the craniocaudal body axis (z coordinate field), which allowed for subdividing the whole-body measures into different subregions typically examined on clinical routine MRI scans (chest, abdomen, and pelvis). (B) BC was quantified from whole-body MRI in over 66,000 individuals from two large population-based cohort studies, the UK Biobank (UKB) (36,317 individuals) and the German National Cohort (NAKO) (30,291 individuals). Bar graphs show age distribution by sex and cohort. BMI = body mass index. (C) After the performance assessment of the fully automated framework, the change in BC measures, distributions, and profiles across age decades were investigated. Age-, sex-, and height-adjusted body composition reference curves were calculated and made publicly available in a web-based z-score calculator (https://circ-ml.github.io).](https://img.auntminnieeurope.com/mindful/smg/workspaces/default/uploads/2026/05/body-comp.XgAjTfPj1W.jpg?auto=format%2Ccompress&fit=crop&h=167&q=70&w=250)
![Overview of the study design. (A) The fully automated deep learning framework was developed to estimate body composition (BC) (defined as subcutaneous adipose tissue [SAT] in liters; visceral adipose tissue [VAT] in liters; skeletal muscle [SM] in liters; SM fat fraction [SMFF] as a percentage; and intramuscular adipose tissue [IMAT] in deciliters) from MRI. The fully automated framework comprised one model (model 1) to quantify different BC measures (SAT, VAT, SM, SMFF, and IMAT) as three-dimensional (3D) measures from whole-body MRI scans. The second model (model 2) was trained to identify standardized anatomic landmarks along the craniocaudal body axis (z coordinate field), which allowed for subdividing the whole-body measures into different subregions typically examined on clinical routine MRI scans (chest, abdomen, and pelvis). (B) BC was quantified from whole-body MRI in over 66,000 individuals from two large population-based cohort studies, the UK Biobank (UKB) (36,317 individuals) and the German National Cohort (NAKO) (30,291 individuals). Bar graphs show age distribution by sex and cohort. BMI = body mass index. (C) After the performance assessment of the fully automated framework, the change in BC measures, distributions, and profiles across age decades were investigated. Age-, sex-, and height-adjusted body composition reference curves were calculated and made publicly available in a web-based z-score calculator (https://circ-ml.github.io).](https://img.auntminnieeurope.com/mindful/smg/workspaces/default/uploads/2026/05/body-comp.XgAjTfPj1W.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
