Dr. Paul Algra, PhD

Clinical News
Should radiologists become informatics professionals?
Nearly every medical discipline depends on imaging informatics, but training and accreditation in this emerging field are still very much in their infancy. This interview article looks at the issues under discussion and the range of courses, qualifications, and diplomas being developed.
February 8, 2018
2018 02 08 19 13 4165 Computer Chip 400
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Top Stories
PET/CT images performed at 10- and 60-minutes following injection of Ga-68 FAPI-46 (mean 181 MBq; range 143–225 MBq).
Molecular Imaging
Early FAPI-PET scans match 60-minute scans for lung cancer staging
By convention, most molecular imaging tracers such as F-18 FDG are injected one hour prior to PET scans to allow time for uptake of the tracer by tumors.
Think more deeply about the structural, procedural, or operational bottlenecks stacking on top of one another, Dr. Rizwan Malik told UKIO delegates.
AI
The great AI debate: Expensive failure or vital prerequisite?
C-index for Cox regression and random survival forests models using two feature sets. Adding historical registry data decreases the C-index for Cox regression but increased it for the random survival forests model, consistent with the non-linear structure in the registry data.
MRI
AI gives a boost to cardiac MRI risk prediction
Flat-detector CT showing catheter position following contralateral middle meningeal artery embolization in a case where ipsilateral access was not possible.
Interventional Radiology
MMA embolization for chronic subdural hematoma: Routine takes shape
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Early FAPI-PET scans match 60-minute scans for lung cancer staging
By Will Morton
By convention, most molecular imaging tracers such as F-18 FDG are injected one hour prior to PET scans to allow time for uptake of the tracer by tumors.
June 10, 2026
PET/CT images performed at 10- and 60-minutes following injection of Ga-68 FAPI-46 (mean 181 MBq; range 143–225 MBq).
The great AI debate: Expensive failure or vital prerequisite?
By Philip Ward
The spotlight fell brightly on AI at Tuesday's plenary session at the U.K. Imaging and Oncology Congress. The global expert panel scrutinized the current status of AI and the challenges ahead.
June 10, 2026
Think more deeply about the structural, procedural, or operational bottlenecks stacking on top of one another, Dr. Rizwan Malik told UKIO delegates.
AI gives a boost to cardiac MRI risk prediction
By Kate Madden Yee
Accurate risk prediction for coronary heart disease helps clinicians guide patient therapy and follow-up.
June 10, 2026
C-index for Cox regression and random survival forests models using two feature sets. Adding historical registry data decreases the C-index for Cox regression but increased it for the random survival forests model, consistent with the non-linear structure in the registry data.
MMA embolization for chronic subdural hematoma: Routine takes shape
By Claudia Tschabuschnig
MMA embolization for chronic subdural hematoma is becoming routine. After eight randomized trials, six positive results, German data now adds to the picture.
June 10, 2026
Flat-detector CT showing catheter position following contralateral middle meningeal artery embolization in a case where ipsilateral access was not possible.
ECIO 2026: interventional oncology's next step
By Claudia Tschabuschnig
At ECIO 2026 in Basel, experts highlighted how multidisciplinary collaboration, patient selection, and evidence generation are shaping the next phase of the specialty.
June 9, 2026
Experts gathered at the European Conference on Interventional Oncology ECIO 2026 in Basel to discuss the latest advances in minimally invasive cancer care.
What's the optimum approach for B3 breast lesions?
By Philip Ward
Certain B3 lesion types should be screened more often, researchers from a top London hospital have asserted at the U.K. Imaging and Oncology Congress (UKIO).
June 9, 2026
Breast Cancer Social
AI may provide early breast cancer alerts from mammograms
By Amerigo Allegretto
Commercial AI systems could provide early alerts for breast cancer by picking out early signs of the disease on mammograms.
June 9, 2026
Screening mammograms and AI score changes are depicted over time in two individuals with screen-detected cancer. Full-field digital mammograms show craniocaudal (top) and mediolateral (bottom) views of the left and right breast. The description below each mammogram indicates whether AI scores from three AI-based computer-aided detection systems (AI-1, AI-2, and AI-3) were above or below the 90th percentile. (A) Mammograms from three screening time points (in 2009, 2011, and 2014) in an individual who was diagnosed in February 2014 (at age 73 years) with a left-sided 25-mm grade 2 invasive breast carcinoma, no special type (arrow). Mammographic breast density was classified as BI-RADS B on all three mammograms. (B) Mammograms from four screening time points (in 2009, 2011, 2013, and 2015) in an individual who was diagnosed in October 2015 (at age 65 years) with a left-sided 45-mm grade 2 lobular carcinoma (arrow). Mammographic breast density was classified as BI-RADS C on all four mammograms. Screen-detected cancers were defined as those diagnosed within 90 days for individuals who were recalled at screening (*).
Tattoo pigments can have significant impact on imaging
By Philip Ward
Tattoos can appear as shadows or artifacts on an x-ray, causing confusion during interpretation. Research presented at the U.K. Imaging and Oncology congress has provided new data on which tattoo inks have the greatest impact.
June 8, 2026
2026 06 08 Tattoos Homepage Image
SERAM 2026: Biparametric MRI cuts time and costs in prostate cancer imaging
By Claudia Tschabuschnig
A study presented at SERAM 2026 suggests that biparametric MRI (bpMRI) can reduce exam time and costs in patients with clinically significant prostate cancer.
June 8, 2026
Biparametric prostate MRI identified clinically significant Gleason 3+4 prostate cancer using T2-weighted imaging, diffusion-weighted imaging, and ADC mapping alone.
SERAM 2026: AI chest triage cuts referrals without raising CT use
By Claudia Tschabuschnig
A real-world implementation study from a Spanish regional hospital suggests that AI-assisted chest radiograph triage may reduce specialist referrals without driving additional CT imaging.
June 4, 2026
An AI system highlights multiple abnormalities on a chest radiograph, including a pulmonary nodule (nódulo pulmonar), pleural effusion (derrame pleural), and alveolar syndrome/consolidation (síndrome alveolar).
AI detects lung cancer nodules well but shows low specificity
By Kate Madden Yee
The finding suggests the models offer “a potential role as adjunctive tools for ruling out malignancy” rather than classifying it.
June 4, 2026
Am 2020 06 26 16 29 2945 Cancer Lung 400
Image-guided focal laser ablation effective for prostate cancer
By Amerigo Allegretto
MRI-directed, ultrasound-guided TPLA may be a promising technique to treat prostate cancer while avoiding radical therapies.
June 3, 2026
Preablation, postablation, and recurrence multiparametric MRI scans depict a 63-year-old man treated with transperineal focal laser ablation (TPLA) for localized prostate cancer. Clinical parameters included an initial prostate-specific antigen (PSA) level of 7.2 ng/mL, a Prostate Imaging Reporting and Data System (PI-RADS) grade 4 lesion (red circles) in the right apical peripheral zone, and a maximum tumor length of 5 mm. MRI-guided targeted biopsy confirmed a Gleason score 3+4 prostate cancer tumor. (A) Pre-ablation axial T2-weighted MRI scan and apparent diffusion coefficient (ADC) image shows the apical PI-RADS 4 lesion (circles). (B) Six-month post-ablation axial T2-weighted MRI scan and ADC image show cystic necrosis (arrows). There was no evidence of recurrence; the PSA level was 1.5 ng/mL. (C) One-year after ablation, the patient’s PSA level had increased to 4.3 ng/mL. Axial T2-weighted MRI scan and the ADC image shows a recurrent lesion (blue circles) in the right apical peripheral zone adjacent to the ablation scar. Targeted biopsy confirmed Gleason score 3+4 prostate cancer, which was classified as in-field recurrence of clinically significant prostate cancer and subsequently re-treated with TPLA. In summary, serial multiplanar MRI demonstrates treatment response after TPLA with post-ablation necrosis, followed by MRI-detected IFR confirmed with biopsy at 12-month follow-up. Multiparametric MRI was performed with a 3.0-T MRI scanner (Skyra; Siemens Healthineers) using T2-weighted, diffusion-weighted, and ADC sequences, with gadobenate dimeglumine contrast material administration (Bracco Diagnostics).
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