Cancer has the most devastating economic effects of any cause of death in the world, according to a report published by the American Cancer Society (ACS) and cancer survivor advocacy group Livestrong in Austin, TX.
Cancer's total economic impact was estimated at $895 billion in 2008, or 1.5% of the world's gross domestic product. This cost did not include direct medical costs, which could potentially double the total economic cost, according to co-authors Rijo John, PhD, and Hana Ross, PhD, research directors at the Atlanta-based ACS.
The World Health Organization (WHO) projects that cancer will become the world's leading cause of death in 2010, followed by heart disease and stroke. In 2008, there were an estimated 7.6 million deaths from cancer, of which 60% represented people living in developing countries.
The cancers that most affected the global economy were lung cancer ($188 billion), colon/rectum cancer ($99 billion), and breast cancer ($88 billion).
The U.S. had the highest economic loss from cancer in absolute dollars of any country in the world, estimated at 1.73% of its gross domestic product. But Hungary lost an estimated 3.05% of its gross domestic product, due to its smaller population size and domestic economy.
The report noted cancers of the lung, bronchus, and trachea as accounting for the largest economic loss -- more than $180 billion. Tobacco will kill 7 million people annually by 2020 and 8 million annually by 2030, with more than 80% of the deaths occurring in low- to middle-income countries if current trends continue, the report predicted.
Due to a lack of screening programs to detect and treat cervical cancer in its early stages, this cancer accounts for more than 10% of the economic loss in low-income countries, second only to mouth and throat cancers. Of the estimated 274,000 women who die from cervical cancer, approximately 88% live in low- and middle-income nations. The report suggested that this finding should give added emphasis to the WHO's initiative to expand cervical cancer prevention and control programs in developing nations.
A "silent pandemic" of cancer is spreading through low- and middle-income countries, with the potential to overwhelm public health systems, threaten social structures, and undermine economic development efforts, according to the report.
Related Reading
U.S. cancer costs double over 20 years, May 10, 2010
Medicare cancer imaging grows at twice rate of overall expenses, April 27, 2010
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![Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.](https://img.auntminnieeurope.com/mindful/smg/workspaces/default/uploads/2026/08/images-radiol250278fig2.APCFLSvX6p.jpg?auto=format%2Ccompress&fit=crop&h=100&q=70&w=100)





![Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.](https://img.auntminnieeurope.com/mindful/smg/workspaces/default/uploads/2026/08/images-radiol250278fig2.APCFLSvX6p.jpg?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)









