Medical imaging modalities are typically used to perform preprocedure planning and postprocedure assessment of patients with severe aortic stenosis undergoing TAVR. A key metric is calculation of extracellular volume fraction (ECV), for which cardiac MRI (CMR) is considered the gold standard.
However, CT angiography (CTA) can also be used for ECV assessment. In the paper presented at SCCT 2022, researchers from Allina Health Minneapolis Heart Institute at Abbott Northwestern Hospital used Ziosoft's Ziostation2 software to perform EVC-CTA assessment and compared it with ECV-CMR.
A group led by Dr. João Cavalcante found that ECV-CTA conducted in conjunction with Ziostation2 demonstrated "excellent" correlation with ECV-CMR in patients with severe aortic stenosis undergoing TAVR evaluation. The application supported the coregistration of precontrast and delayed acquisitions and created a multisegmented ECV-CT map,
This technology helped enable ECV-CT assessment making it a viable, noninvasive approach to assess myocardial fibrosis and potential prescreening of cardiac amyloidosis during preplanning TAVR or post-TAVR procedures, Cavalcante found.
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